longevity - The Compound Codex

Metformin title card: foil tablets beside a research folder tied shut and a blank clipboard, ringed by an empty axis, a dumbbell with a downward arrow, an empty jar and a prescription slip.

longevity

Metformin for slowing aging

The trial meant to settle this has never enrolled anyone. The question that has been tested twice is whether metformin blunts what exercise does.

Rapamycin title card: an amber pill bottle on a lab bench with a mouse cage behind it, ringed by a mouse, a lone data point on an empty axis, a crossed shield and a prescription slip.

longevity

Rapamycin for slowing aging

The best lifespan result ever produced in mice, and a single 114-person human trial whose positive findings were confined to women on the higher dose.

Title card reading Resveratrol, with dark grapes, a glass of red wine and a labelled vial, ringed by a molecular pathway and diverging arrows.

longevity

Resveratrol for metabolic health

Does resveratrol improve glycemic control in people with type 2 diabetes?

Title card reading NMN, with an hourglass beside a labelled bottle, ringed by a rising molecule icon and a flat horizontal line.

longevity

NMN for slowing aging

Does taking NMN improve any measured health outcome in humans?